Up-to date list of oral antihyperglycemic drugs and Insulin analogs by classes, including Thiazolidinediones, Sulfonylureas, Meglitinides, GLP-1 Analogues, DPP-4 Inhibitors, SGLT-2 Inhibitors, and combination products. A model-based meta-analysis of 24 antihyperglycemic drugs for type 2 diabetes: comparison of treatment effects at therapeutic doses Type II diabetes often may be treated with oral hypoglycemic or antihyperglycemic drugs instead of with insulin. The sulfonylureas, for example, stimulate the insulin-secreting beta cells of the pancreas to produce more insulin.
Oral antihyperglycemic agents lower glucose levels in the blood. They are commonly used in the treatment of diabetes mellitus. When insulin is needed for patients with type 2 diabetes, glycemic control can often be achieved with basal insulin combined with non- insulin antihyperglycemic medications, although some patients may require prandial (bolus dosing at meals) insulin. Antihyperglycemic medications are designed to help control blood sugar levels in individuals with diabetes.
antihyperglycemic drugs, These medications work in various ways to reduce the high levels of blood sugar that characterize diabetes. Some antihyperglycemics increase insulin production in the pancreas. Oral antihyperglycemic medications (see table Characteristics of Oral Antihyperglycemics) are a mainstay of treatment for type 2 diabetes mellitus, along with injectable glucagon-like peptide-1 (GLP-1) receptor agonists.
